Article
APOE genotype, hippocampus, and cognitive markers of Alzheimer's disease in American Indians: Data from the Strong Heart Study.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Dec 2022
Suchy-Dicey Astrid, Howard Barbara, Longstreth W T, Reiman Eric M, Buchwald Dedra
Abstract excerpt
BACKGROUND: The apolipoprotein E (APOE) ε4 allele confers higher risk of neurodegeneration and Alzheimer's disease (AD), but differs by race/ethnicity. We examined this association in American Indians. METHODS: The Strong Heart Study is a population-based cohort of American Indians who were 64 to 95 years of age in 2010 to 2013. APOE ε4 status, brain imaging, and neuropsychological testing was collected in...
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