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Article

Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2017

Bressler Jan, Mosley Thomas H, Penman Alan, Gottesman Rebecca F, Windham Beverly Gwen, Knopman David S, Wruck Lisa M, Boerwinkle Eric

Abstract excerpt

Alzheimer's disease (AD) is the most common form of dementia and is characterized by impairment in memory, behavioral changes, and gradual loss of autonomy. Since there is a long latent period prior to diagnosis, the aim of this study was to determine whether twenty single nucleotide polymorphisms identified in genome-wide association analyses of AD are associated with cognitive change in 8,320 white and 2,039...

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Source

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Identifiers

PMID: 27781389
DOI: 10.1002/ajmg.b.32509
PMCID: PMC5935000

Genes

APOE
CLU
NME8
ZCWPW1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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