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Article

Regulation of the cytosolic DNA-sensing system in innate immunity: a current view.

Current opinion in immunology - 1 Feb 2009

Yanai Hideyuki, Savitsky David, Tamura Tomohiko, Taniguchi Tadatsugu

Abstract excerpt

The sensing of nucleic acids by pattern recognition receptors is a central feature of innate immunity and is mediated by two types of receptors, Toll-like receptors and cytosolic receptors. Indeed, DNA, be it pathogen-derived or self-derived, can potently trigger the innate immune system; and much attention has been focused on the regulation of the DNA-sensing system(s) in the context of protective and...

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Source

Identifiers

PMID: 19362700
DOI: 10.1016/j.coi.2009.01.005

Genes

TLR9
ZBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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