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Article

TPH2 gene variants and anxiety during alcohol detoxification outcome.

Psychiatry research - 15 May 2009

Serretti Alessandro, Liappas Ioannis, Mandelli Laura, Albani Diego, Forloni Gianluigi, Malitas Petros, Piperi Christina, Politis Antonis, Tzavellas Elias O, Papadopoulou-Daifoti Zeta, Zisaki Aikaterini, Prato Francesca, Batelli Sara, Polito Letizia, De Ronchi Diana, Kalofoutis Anastasios

Abstract excerpt

Clinical outcome of alcoholism may be partly under genetic control. The serotonergic system is involved in alcohol intake, and it has been widely investigated in alcohol dependence. Recently, attention has been focused on the neuronal tryptophan hydroxylase 2 gene (TPH2). TPH2 variants have been consistently associated with anxiety-related traits; since anxiety is critical for alcohol dependence treatment, in the...

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Source

Identifiers

PMID: 19361870
DOI: 10.1016/j.psychres.2007.12.006

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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