Article
Genetic polymorphisms of UGT1A7 and cancer risk: evidence from 21 case-control studies.
Cancer investigation - 1 Dec 2011
Lu Pei-Hua, Chen Min-Bin, Wu Xiao-Yang, Gu Jin-Hua, Liu Yuan, Gu Rong-Min
Abstract excerpt
The aim of our meta-analysis was to assess the association between UGT1A7 polymorphisms and cancer risk. Case?control studies containing available polymorphic alleles (UGT1A7*1,*2,*3, and*4) and genotypes categorized according to enzymatic activity (High, Intermediate, and Low) were chosen to assess this association. Twenty-one case?control studies were identified. Meta-analysis indicated that UGT1A7 had a...
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