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Article

GEPT extract reduces Abeta deposition by regulating the balance between production and degradation of Abeta in APPV717I transgenic mice.

Current Alzheimer research - 1 Apr 2009

Tian Jinzhou, Shi Jing, Zhang Leiming, Yin Junxiang, Hu Quan, Xu Yi, Sheng Shuli, Wang Pengwen, Ren Ying, Wang Rong, Wang Yongyan

Abstract excerpt

BACKGROUND: Accumulation of beta-amyloid peptide (Abeta) in the brain is a primary influence driving Alzheimer's disease (AD) pathogenesis. The disease process, including formation of neurofibrillary tangles containing tau protein, is proposed to result from an imbalance between production and clearance of Abeta. A major therapeutic strategy for AD should be to decrease deposition of Abeta by the inhibition of...

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Identifiers

PMID: 19355846
DOI: 10.2174/156720509787602942

Genes

APP
IDE
BACE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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