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Article

Grape derived polyphenols attenuate tau neuropathology in a mouse model of Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2010

Wang Jun, Santa-Maria Ismael, Ho Lap, Ksiezak-Reding Hanna, Ono Kenjiro, Teplow David B, Pasinetti Giulio Maria

Abstract excerpt

Aggregation of microtubule-associated protein tau into insoluble intracellular neurofibrillary tangles is a characteristic hallmark of Alzheimer's disease (AD) and other neurodegenerative diseases, including progressive supranuclear palsy, argyrophilic grain disease, corticobasal degeneration, frontotemporal dementias with Parkinsonism linked to chromosome 17, and Pick's disease. Tau is abnormally...

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Identifiers

PMID: 20858961
DOI: 10.3233/JAD-2010-101074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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