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Article

A novel mechanism of antagonism between ATP-dependent chromatin remodeling complexes regulates RNR3 expression.

Molecular and cellular biology - 1 Jun 2009

Tomar Raghuvir S, Psathas James N, Zhang Hesheng, Zhang Zhengjian, Reese Joseph C

Abstract excerpt

Gene expression depends upon the antagonistic actions of chromatin remodeling complexes. While this has been studied extensively for the enzymes that covalently modify the tails of histones, the mechanism of how ATP-dependent remodeling complexes antagonize each other to maintain the proper level of gene activity is not known. The gene encoding a large subunit of ribonucleotide reductase, RNR3, is regulated by...

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Identifiers

PMID: 19349301
DOI: 10.1128/MCB.01741-08
PMCID: PMC2698743

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