Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Description and validation of high-throughput simultaneous genotyping and mutation scanning by high-resolution melting curve analysis.

Human mutation - 1 Jun 2009

Nguyen-Dumont Tú, Calvez-Kelm Florence Le, Forey Nathalie, McKay-Chopin Sandrine, Garritano Sonia, Gioia-Patricola Lydie, De Silva Deepika, Weigel Ron, Sangrajrang Suleeporn, Lesueur Fabienne, Tavtigian Sean V

Abstract excerpt

Mutation scanning using high-resolution melting curve analysis (HR-melt) is an effective and sensitive method to detect sequence variations. However, the presence of a common SNP within a mutation scanning amplicon may considerably complicate the interpretation of results and increase the number of samples flagged for sequencing by interfering with the clustering of samples according to melting profiles. A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia Telangiectasia Mutated Proteins
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Cycle Proteins

Share to DNA-Binding Proteins

Share to Nucleic Acid Denaturation

Share to Protein Serine-Threonine Kinases

Share to Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 19347964
DOI: 10.1002/humu.20949
PMCID: PMC3478947

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Description and validation of high-throughput simultaneous genotyping and mutation scanning by high-resolution melting curve analysis.PMID 19347964Read ↗

Simultaneous mutation scanning and genotyping by high-resolution DNA melting analysis.Semantic proximity Read ↗

Genotyping DNA Variants with High-Resolution Melting Analysis.Semantic proximity Read ↗

High-resolution DNA melting analysis in clinical research and diagnostics.Semantic proximity Read ↗

Rapid and sensitive detection of BRCA1/2 mutations in a diagnostic setting: comparison of two high-resolution melting platforms.Semantic proximity Read ↗

Multiplexed High Resolution Melting Assay for Versatile Sample Tracking in a Diagnostic and Research Setting.Semantic proximity Read ↗

Mutation scanning using high-resolution melting.Semantic proximity Read ↗

Genotyping of frequent BRCA1/2 SNPs with unlabeled probes: a supplement to HRMCA mutation scanning, allowing the strong reduction of sequencing burden.Semantic proximity Read ↗

Haplotype and Presence-Absence Variation Analysis Using High-Resolution Melting (HRM) Analysis for Genotyping Genes of Interest.Semantic proximity Read ↗

High-resolution DNA melting analysis for simultaneous mutation scanning and genotyping in solution.Semantic proximity Read ↗

High-resolution melting analysis of single nucleotide polymorphisms.Semantic proximity Read ↗

High-resolution melting analysis for genotyping of the myotonic dystrophy type 1 associated Alu insertion/deletion polymorphism.Semantic proximity Read ↗

Genotyping by high-resolution melting analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.