Article
Association of CYP1A1*2 polymorphisms with breast cancer risk: a case control study.
Indian journal of medical sciences - 1 Jan 2009
Surekha D, Sailaja K, Rao D Nageswara, Padma T, Raghunadharao D, Vishnupriya S
Abstract excerpt
BACKGROUND: The Cytochrome P-4501A1 (CYP1A1) gene, located on chromosome 15q, is involved in the metabolism of carcinogens mainly polycyclic aromatic hydrocarbons as well as estrogen. It is considered as candidate gene for low-penetrance breast cancer susceptibility. Hence the present study aims to discuss the role of CYP1A1 polymorphisms in breast cancer. MATERIALS AND METHODS: A total of 250 breast cancer...
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