Article
Aberrant development of neuromuscular junctions in glycosylation-defective Large(myd) mice.
Neuromuscular disorders : NMD - 1 May 2009
Herbst Ruth, Iskratsch Thomas, Unger Ewald, Bittner Reginald E
Abstract excerpt
Mice deficient in the glycosyltransferase Large are characterized by severe muscle and central nervous system abnormalities. In this study, we show that the formation and maintenance of neuromuscular junctions in Large(myd) mice are greatly compromised. Neuromuscular junctions are not confined to...
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