Article
Formation of complex AChR aggregates in vitro requires alpha-dystrobrevin.
Developmental neurobiology - 1 Apr 2009
Pawlikowski Bradley T, Maimone Margaret M
Abstract excerpt
Efficient function at the neuromuscular junction requires high-density aggregates of acetylcholine receptors (AChRs) to be precisely aligned with the motor nerve terminal. A collaborative effort between the motor neuron and muscle intrinsic factors drives the formation and maintenance of these AChR aggregates. alpha-Dystrobrevin (alpha DB), a cytoplasmic protein found at the postsynaptic membrane, has been...
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