Article
Mutation of Large, which encodes a putative glycosyltransferase, in an animal model of muscular dystrophy.
Biochimica et biophysica acta - 19 Dec 2002
Grewal Prabhjit K, Hewitt Jane E
Abstract excerpt
The myodystrophy (myd) mutation arose spontaneously and has an autosomal recessive mode of inheritance. Homozygous mutant mice display a severe, progressive muscular dystrophy. Using a positional cloning approach, we identified the causative mutation in myd as a deletion within the Large gene, wh...
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