Article
Olfactory stem cells can be induced to express chondrogenic phenotype in a rat intervertebral disc injury model.
The spine journal : official journal of the North American Spine Society - 1 Jul 2009
Murrell Wayne, Sanford Emma, Anderberg Leif, Cavanagh Brenton, Mackay-Sim Alan
Abstract excerpt
BACKGROUND: In humans, lower back pain is one of the most common causes of morbidity. Many studies implicate degeneration of intervertebral discs as the cause. In the normal intervertebral disc, the nucleus pulposus exerts a hydrostatic pressure against the constraining annulus fibrosus, which allows the disc to maintain flexibility between adjacent vertebrae, while absorbing necessary compressive forces. The...
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