Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of neural and neurotrophic markers in nucleus pulposus cells isolated from degenerated intervertebral disc.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Sept 2012

Navone Stefania E, Marfia Giovanni, Canzi Laura, Ciusani Emilio, Canazza Alessandra, Visintini Sergio, Campanella Rolando, Parati Eugenio A

Abstract excerpt

Intervertebral disc (IVD) degeneration is a common disorder of the lower spine. Since it is caused by loss of cellularity, there is interest in the comprehension of the cellular phenotypes. This study aimed to verify if stem cells isolated from nucleus pulposus of intervertebral discs (NPs-IVD), which may express neurogenic properties, may be implicated in IVD disease. NPs-IVD isolated from 14 human pathological...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acid Sensing Ion Channels
Share to Intervertebral Disc

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intervertebral Disc Degeneration

Share to Mesenchymal Stem Cells

Share to Neurogenesis

Share to Receptor, trkA

Share to Receptor, trkB

Share to Sodium Channels

Source

Identifiers

PMID: 22374745
DOI: 10.1002/jor.22098

Genes

IVD
ASIC3
BDNF
GFAP
MAP2
NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of neural and neurotrophic markers in nucleus pulposus cells isolated from degenerated intervertebral disc.PMID 22374745Read ↗

Regenerative potential of human nucleus pulposus resident stem/progenitor cells declines with ageing and intervertebral disc degenerationSemantic proximity Read ↗

Understanding nucleus pulposus cell phenotype: a prerequisite for stem cell based therapies to treat intervertebral disc degeneration.Semantic proximity Read ↗

Notochordal Cell-Based Treatment Strategies and Their Potential in Intervertebral Disc RegenerationSemantic proximity Read ↗

Identifying molecular phenotype of nucleus pulposus cells in human intervertebral disc with aging and degeneration.Semantic proximity Read ↗

Coming together is a beginning: The making of an intervertebral discSemantic proximity Read ↗

An understanding of intervertebral disc development, maturation and cell phenotype provides clues to direct cell-based tissue regeneration therapies for disc degeneration.Semantic proximity Read ↗

Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting.Semantic proximity Read ↗

A Brief Review of the Degenerative Intervertebral Disc Disease.Semantic proximity Read ↗

Functional differentiation of Human Dental Pulp Stem Cells into neuron-like cells exhibiting electrophysiological activitySemantic proximity Read ↗

Functional differentiation of Human Dental Pulp Stem Cells into neuron-like cells exhibiting electrophysiological activitySemantic proximity Read ↗

Identification of novel nucleus pulposus markersSemantic proximity Read ↗

The nucleus pulposus microenvironment in the intervertebral disc: the fountain of youth?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.