Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue.

Arthritis research & therapy - 1 Jan 2009

Le Maitre Christine L, Baird Pauline, Freemont Anthony J, Hoyland Judith A

Abstract excerpt

INTRODUCTION: The decreased disc height characteristic of intervertebral disc (IVD) degeneration has often been linked to low back pain, and thus regeneration strategies aimed at restoring the disc extracellular matrix and ultimately disc height have been proposed as potential treatments for IVD degeneration. One such therapy under investigation by a number of groups worldwide is the use of autologous mesenchymal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Cells
Share to Extracellular Matrix

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescent Antibody Technique

Share to In Situ Hybridization

Share to In Vitro Techniques

Share to Intervertebral Disc

Share to Mesenchymal Stem Cell Transplantation

Share to Mesenchymal Stem Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 19210770
DOI: 10.1186/ar2611
PMCID: PMC2688252

Genes

IVD
MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue.PMID 19210770Read ↗

Identification of novel nucleus pulposus markersSemantic proximity Read ↗

Notochordal cell conditioned medium stimulates mesenchymal stem cell differentiation toward a young nucleus pulposus phenotypeSemantic proximity Read ↗

Intervertebral Disc Cell–Mediated Mesenchymal Stem Cell DifferentiationSemantic proximity Read ↗

Regenerative potential of human nucleus pulposus resident stem/progenitor cells declines with ageing and intervertebral disc degenerationSemantic proximity Read ↗

Understanding nucleus pulposus cell phenotype: a prerequisite for stem cell based therapies to treat intervertebral disc degeneration.Semantic proximity Read ↗

Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cellsSemantic proximity Read ↗

Differentiation of Pluripotent Stem Cells into Nucleus Pulposus Progenitor Cells for Intervertebral Disc RegenerationSemantic proximity Read ↗

Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy.Semantic proximity Read ↗

Nonviral Gene Delivery of Growth and Differentiation Factor 5 to Human Mesenchymal Stem Cells Injected into a 3D Bovine Intervertebral Disc Organ Culture SystemSemantic proximity Read ↗

Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting.Semantic proximity Read ↗

Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation.Semantic proximity Read ↗

Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.