Article
Identification of a splice variant of the metal-responsive transcription factor MTF-1 in common carp.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP - 1 Jul 2009
Ferencz Agnes, Hermesz Edit
Abstract excerpt
Transactivation of the expression of metallothionein genes involves the Metal-responsive Transcription Factor (MTF-1). We report here the identification of mtf-1.1a, the first known splice variant of mtf-1.1 mRNA, in common carp (Cyprinus carpio). The lack of a 103 nt internal segment results in a frame shift, causing the early termination of translation. mtf-1.1a mRNA encodes a protein consisting of the first...
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