Article
Inhibition of endogenous MTF-1 signaling in zebrafish embryos identifies novel roles for MTF-1 in development.
Biochimica et biophysica acta - 1 Sept 2014
O'Shields Britton, McArthur Andrew G, Holowiecki Andrew, Kamper Martin, Tapley Jeffrey, Jenny Matthew J
Abstract excerpt
The metal responsive element-binding transcription factor-1 (MTF-1) responds to changes in cellular zinc levels caused by zinc exposure or disruption of endogenous zinc homeostasis by heavy metals or oxygen-related stress. Here we report the functional characterization of a complete zebrafish MTF-1 in comparison with the previously identified isoform lacking the highly conserved cysteine-rich motif...
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