Article
Association of the growth hormone receptor gene polymorphisms with mandibular height in a Korean population.
Archives of oral biology - 1 Jun 2009
Kang Eun Hee, Yamaguchi Tetsutaro, Tajima Atsushi, Nakajima Toshiaki, Tomoyasu Yoko, Watanabe Miyuki, Yamaguchi Masaaki, Park Soo Byung, Maki Koutaro, Inoue Ituro
Abstract excerpt
Growth hormone receptor gene (GHR) is one of the likely candidates for determining morphological traits, because GH is a key regulator of bone growth. The genetic association of GHR in exon 10 with mandibular ramus height has been found in different populations, Japanese and Chinese. On the other hand, two common isoforms of GHR, one full-length (fl-GHR) and the other lacking the extracellular domain encoded by...
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