Role of the rs6184 growth hormone receptor gene polymorphism in mandibular morphogenesis.

doi:10.1016/j.ejwf.2025.02.002

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Article

Role of the rs6184 growth hormone receptor gene polymorphism in mandibular morphogenesis.

Journal of the World federation of orthodontists - 1 Aug 2025

George Ashwin Mathew, Jayaseelan Vijayashree Priyadharsini, Felicita A Sumathi, Raju Rebekah, Subramanian Aravind Kumar

Abstract excerpt

BACKGROUND: Polymorphisms in the growth hormone receptor (GHR) gene influence the craniofacial system by affecting the growth of the mandibular body length and ramal height, with significant variations observed across different ethnic populations. This study investigated the relationship between a single nucleotide polymorphism (rs6184) in the GHR gene and its effects on mandibular morphogenesis in a Dravidian...

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PMID: 40210515
DOI: 10.1016/j.ejwf.2025.02.002

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