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Article

The P561T polymorphism of the growth hormone receptor gene has an inhibitory effect on mandibular growth in young children.

European journal of orthodontics - 1 Oct 2009

Sasaki Yasunori, Satoh Kyoko, Hayasaki Haruaki, Fukumoto Satoshi, Fujiwara Taku, Nonaka Kazuaki

Abstract excerpt

P561T heterozygous missense mutation in the growth hormone receptor (GHR) is a candidate genetic polymorphism (single-nucleotide polymorphism) for human mandibular growth. The purpose of this study was to assess whether this mutation affects mandibular growth during early childhood. The difference in mandibular growth between P561T heterozygous and wild-type individuals was analysed by cephalometric measurements...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19447840
DOI: 10.1093/ejo/cjp017

Genes

GHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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