Article
GHR and IGF2R genes may contribute to normal variations in craniofacial dimensions: Insights from an admixed population.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics - 1 Nov 2020
Marañón-Vásquez Guido Artemio, Vieira Alexandre R, de Carvalho Ramos Alice Gomes, Dantas Beatriz, Romano Fábio Lourenço, Palma-Dibb Regina Guenka, Arid Juliana, Carpio Karla, Nelson-Filho Paulo, de Rossi Andiara, Scariot Rafaela, Levy Simone Carvalho, Antunes Lívia Azeredo A, Antunes Leonardo Santos, Küchler Erika C
Abstract excerpt
INTRODUCTION: This study aimed to determine whether single nucleotide polymorphisms in the growth hormone receptor (GHR) and insulin-like growth factor 2 receptor (IGF2R) genes are associated with different craniofacial phenotypes. METHODS: A total of 596 orthodontic and 98 orthognathic patients from 4 cities in Brazil were included for analyses. Angular and linear cephalometric measurements were obtained, and...
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