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The Genetics of Autoimmune Thyroid Disease

2 Apr 2009

Abstract excerpt

Recent studies have confirmed that polymorphisms in several genes confer susceptibility for the development of autoimmune thyroid disease, and that of these HLA-DR alleles, and the genes encoding CTLA-4, PTPN22, FCRL3, and probably the IL-2 receptor all have associations with other autoimmune disorders, indicating that they provide a lowering of the background threshold for the development of autoimmunity. Other...

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PMID: 19343617
DOI: 10.1055/s-0029-1214415

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