Article
Autoimmunity in thyroid disease.
European journal of nuclear medicine and molecular imaging - 1 Aug 2002
Collins Joanne, Gough Stephen
Abstract excerpt
The autoimmune thyroid diseases, Graves' disease and autoimmune hypothyroidism, represent the two ends of a disease spectrum where an immune response is directed against the thyroid gland. In Graves' disease, antibodies directed against the thyrotropin receptor (TSH-R) lead to the development of glandular overactivity, while in autoimmune hypothyroidism, cell-mediated and humoral thyroid injury leads to...
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