Autoimmune thyroid diseases: genetic susceptibility of thyroid-specific genes and thyroid autoantigens contributions.

doi:10.1111/j.1744-313X.2009.00830.x

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Article

Autoimmune thyroid diseases: genetic susceptibility of thyroid-specific genes and thyroid autoantigens contributions.

International journal of immunogenetics - 1 Apr 2009

Hadj-Kacem H, Rebuffat S, Mnif-Féki M, Belguith-Maalej S, Ayadi H, Péraldi-Roux S

Abstract excerpt

Autoimmune thyroid diseases are common polygenic multifactorial disorders with the environment contributing importantly to the emergence of the disease phenotype. Some of the disease manifestations, such as severe thyroid-associated ophthalmopathy, pretibial myxedema and thyroid antigen/antibody immune complex nephritis are unusual to rare. The spectrum of autoimmune thyroid diseases includes: Graves' disease...

Topics

Autoantibodies
Autoantigens
Genetic Predisposition to Disease
Humans
Iodide Peroxidase
Receptors, Thyrotropin
Symporters
Thyroglobulin
Thyroiditis, Autoimmune

Source

Open in PubMed

Identifiers

PMID: 19284442
DOI: 10.1111/j.1744-313X.2009.00830.x

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