Article
Genetic susceptibility in thyroid autoimmunity.
Pediatric endocrinology reviews : PER - 1 Sept 2005
Ban Yoshiyuki, Tomer Yaron
Abstract excerpt
The autoimmune thyroid diseases (AITD) include Graves' disease (GD) which manifests in hyperthyroidism and Hashimoto's thyroiditis (HT), manifesting as hypothyroidism. Genetic susceptibility in combination with external factors (e.g. dietary iodine) are believed to initiate the autoimmune response to thyroid antigens in AITD. Indeed, there is solid epidemiological data to support a strong genetic influence on the...
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