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New Genetic Insights from Autoimmune Thyroid Disease

1 Jan 2012

Abstract excerpt

The autoimmune thyroid diseases (AITDs) (Graves' disease and Hashimoto's thyroiditis) are complex genetic diseases which most likely have more than 20 genes contributing to the clinical phenotypes. To date, the genes known to be contributing fall into two categories: immune regulatory genes (including HLA, CTLA4, PTPN22, CD40, CD25, and FCRL3) and thyroid-specific genes (TG and TSHR). However, none of these genes...

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PMID: 22530160
DOI: 10.1155/2012/623852

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