Article
Hygromycin- and paromomycin-resistant mutants of Aspergillus nidulans alter translational fidelity.
Current genetics - 1 Aug 1991
Martinelli S D, Sheikh A
Abstract excerpt
Mutants of Aspergillus nidulans resistant to the aminoglycoside antibiotics paromomycin and hygromycin B have been isolated and their growth characteristics are described here. Most paromomycin mutants were cross-resistant to hygromycin and geneticin. All the hygromycin-resistant mutants were slightly cross-resistant to geneticin. Out of the 15 mutants tested 14 had drug-resistant ribosomes in vitro and all 12 of...
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