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Article

Interaction between 16S ribosomal RNA and ribosomal protein S12: differential effects of paromomycin and streptomycin.

Biochimie - 1 Dec 1991

O'Connor M, De Stasio E A, Dahlberg A E

Abstract excerpt

Strains containing a series of restrictive and non-restrictive mutations in ribosomal protein S12 have been transformed with plasmids carrying the rrnB operon with mutations at positions 1409 and 1491 in 16S rRNA. The effects of the double-mutant constructs have been measured by growth rate, paromomycin and streptomycin sensitivity, resistance and dependence. The results demonstrate a functional interaction...

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PMID: 1725261
DOI: 10.1016/0300-9084(91)90183-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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