Article
A UV-induced mutation in neurospora that affects translational regulation in response to arginine.
Genetics - 1 Jan 1996
Freitag M, Dighde N, Sachs M S
Abstract excerpt
The Neurospora crassa arg-2 gene encodes the small subunit of arginine-specific carbamoyl phosphate synthetase. The levels of arg-2 mRNA and mRNA translation are negatively regulated by arginine. An upstream open reading frame (uORF) in the transcript's 5' region has been implicated in arginine-specific control. An arg-2-hph fusion gene encoding hygromycin phosphotransferase conferred arginine-regulated...
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