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Article

A novel locus for adolescent idiopathic scoliosis on chromosome 12p.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Oct 2009

Raggio Cathleen L, Giampietro Philip F, Dobrin Seth, Zhao Chengfeng, Dorshorst Donna, Ghebranious Nader, Weber James L, Blank Robert D

Abstract excerpt

Adolescent idiopathic scoliosis (AIS) is a common disorder with strong evidence for genetic predisposition. Quantitative trait loci (QTLs) for AIS susceptibility have been identified on chromosomes. We performed a genome-wide genetic linkage scan in seven multiplex families using 400 marker loci with a mean spacing of 8.6 cM. We used Genehunter Plus to generate linkage statistics, expressed as homogeneity (HLOD)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19340878
DOI: 10.1002/jor.20885
PMCID: PMC4120267

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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