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Article

ZAP-70, IgVh, and cytogenetics for assessing prognosis in chronic lymphocytic leukemia.

Cancer biomarkers : section A of Disease markers - 1 Jan 2010

Trojani Alessandra, Montillo Marco, Nichelatti Michele, Tedeschi Alessandra, Colombo Chiara, Veronese Silvio, Mura Maria Angela, Ricci Francesca, Scarpati Barbara, Colosimo Anna, Lodola Milena, Morra Enrica

Abstract excerpt

BACKGROUND: New prognostic factors such as IgVh mutational status, ZAP-70 protein expression and cytogenetic abnormalities have shown to offer important prognostic information for patients with chronic lymphocytic leukemia (CLL). Our aim was to evaluate the optimal cut-off for IgVh mutational status, ZAP-70 expression and cytogenetic abnormalities in association with disease progression defined as the need for...

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Area Under Curve
Cell Separation
Cytogenetics
Immunoglobulin Heavy Chains
Immunoglobulin Variable Region

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukemia, Lymphocytic, Chronic, B-Cell

ZAP-70 Protein-Tyrosine Kinase

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Identifiers

PMID: 20164537
DOI: 10.3233/CBM-2009-0114
PMCID: PMC12922840

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