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Article

TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes.

The Journal of biological chemistry - 25 Sept 2009

Gazit Kfir, Moshonov Sandra, Elfakess Rofa, Sharon Michal, Mengus Gabrielle, Davidson Irwin, Dikstein Rivka

Abstract excerpt

The major core promoter-binding factor in polymerase II transcription machinery is TFIID, a complex consisting of TBP, the TATA box-binding protein, and 13 to 14 TBP-associated factors (TAFs). Previously we found that the histone H2A-like TAF paralogs TAF4 and TAF4b possess DNA-binding activity. Whether TAF4/TAF4b DNA binding directs TFIID to a specific core promoter element or facilitates TFIID binding to...

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Source

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Identifiers

PMID: 19635797
DOI: 10.1074/jbc.M109.011486
PMCID: PMC2785316

Genes

TAF4
TAF12
TBP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes.PMID 19635797Read ↗

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