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Article

Molecular pathways mediating MDS/AML with focus on AML1/RUNX1 point mutations.

Journal of cellular physiology - 1 Jul 2009

Harada Yuka, Harada Hironori

Abstract excerpt

AML1/RUNX1 point mutations have been identified in myelodysplastic syndrome (MDS) and MDS-related acute myeloid leukemia (AML), or MDS/AML, and are distributed throughout the full length of AML1/RUNX1. Gene mutation is proposed to be one of the disease-defining genetic abnormalities of MDS/AML. M...

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Share to Antigens, CD34
Share to Cell Transformation, Neoplastic
Share to Core Binding Factor Alpha 2 Subunit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to Hematopoietic Stem Cells

Share to Leukemia, Myeloid, Acute

Share to Myelodysplastic Syndromes

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Source

Identifiers

PMID: 19334039
DOI: 10.1002/jcp.21769

Genes

RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19334039-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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