Article
Single-copy chromosomal integration systems for Francisella tularensis.
Microbiology (Reading, England) - 1 Apr 2009
LoVullo Eric D, Molins-Schneekloth Claudia R, Schweizer Herbert P, Pavelka Martin S
Abstract excerpt
Francisella tularensis is a fastidious Gram-negative bacterium responsible for the zoonotic disease tularemia. Investigation of the biology and molecular pathogenesis of F. tularensis has been limited by the difficulties in manipulating such a highly pathogenic organism and by a lack of genetic tools. However, recent advances have substantially improved the ability of researchers to genetically manipulate this...
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