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Article

Use of transposon-transposase complexes to create stable insertion mutant strains of Francisella tularensis LVS.

Applied and environmental microbiology - 1 Nov 2004

Kawula Thomas H, Hall Joshua D, Fuller James R, Craven Robin R

Abstract excerpt

Francisella tularensis is a highly virulent zoonotic bacterial pathogen capable of infecting numerous different mammalian species, including humans. Elucidation of the pathogenic mechanisms of F. tularensis has been hampered by a lack of tools to genetically manipulate this organism. Herein we describe the use of transposome complexes to create insertion mutations in the chromosome of the F. tularensis live...

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Source

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Identifiers

PMID: 15528561
DOI: 10.1128/AEM.70.11.6901-6904.2004
PMCID: PMC525197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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