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Article

Fitness Cost of VanA-Type Vancomycin Resistance in Methicillin-Resistant <i>Staphylococcus aureus</i>

31 Mar 2009

Abstract excerpt

We have quantified the biological cost of VanA-type glycopeptide resistance due to the acquisition of the resistance operon by methicillin-resistant Staphylococcus aureus (MRSA) from Enterococcus sp. Exponential growths of recipient strain HIP11713, its transconjugant VRSA-1, VRSA-5, and VRSA-6 were compared in the absence or, except for HIP11713, in the presence of vancomycin. Induction of resistance was...

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PMID: 19332680
DOI: 10.1128/aac.01702-08

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