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Repeated Exposure of Vancomycin to Vancomycin-Susceptible Staphylococcus aureus (VSSA) Parent Emerged VISA and VRSA Strains with Enhanced Virulence Potentials.

Journal of microbiology (Seoul, Korea) - 1 Jul 2024

Nguyen An, Roy J Jean Sophy, Kim Ji-Hoon, Yun Kyung-Hee, Lee Wonsik, Kim Kyeong Kyu, Kim Truc, Chaurasia Akhilesh Kumar

Abstract excerpt

The emergence of resistance against the last-resort antibiotic vancomycin in staphylococcal infections is a serious concern for human health. Although various drug-resistant pathogens of diverse genetic backgrounds show higher virulence potential, the underlying mechanism behind this is not yet clear due to variability in their genetic dispositions. In this study, we investigated the correlation between...

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PMID: 38814539
DOI: 10.1007/s12275-024-00139-8

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