Article
Diversifying and stabilizing selection of sialidase and N-acetylneuraminate catabolism in Mycoplasma synoviae.
Journal of bacteriology - 1 Jun 2009
May Meghan, Brown Daniel R
Abstract excerpt
Sialidase activity varies widely among strains and tends to correlate with strain virulence in the avian pathogen Mycoplasma synoviae. To characterize the forms of selection acting on enzymes required for sialic acid scavenging and catabolism, the ratios of nonsynonymous (K(a)) to synonymous (K(s)) mutation frequency were calculated for codons in the sialidase gene of 16 strains of M. synoviae and for its nearly...
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