Article
Mannose binding lectin (+54) exon 1 gene polymorphism in Tunisian kidney transplant patients.
Transplantation proceedings - 1 Mar 2009
Gorgi Y, Sfar I, Aouadi H, Makhlouf M, Abderrahim E, Jendoubiayed S, Bardi R, Ben Abdallah T, Ayed K
Abstract excerpt
Mannose-binding lectin (MBL), a collagen-like serum protein, is a key component of innate immunity. MBL binding to carbohydrates present on pathogens mediates lectin-dependent activation of the complement pathway. There is growing interest in the importance of innate immunity in host defense, particularly when adaptive immunity is compromised. Three single nucleotide polymorphisms (SNPs) of the MBL gene have been...
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