Article
Expression profiling and interferon-beta regulation of liver metastases in colorectal cancer cells.
Clinical & experimental metastasis - 1 Jan 2002
Zimmer Regis, Thomas Peter
Abstract excerpt
Liver metastasis is the major cause of death among colorectal cancer patients. Many gene products have been associated with the colon cancer cells' ability to metastasize to the liver, including carcinoembryonic antigen (CEA) and mucins. In this study we examined changes in expression of 384 genes in a model of human colorectal cancer metastasis in nude mice. Using DNA microarrays, we compared expression between...
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