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Radiation-attenuated schistosome vaccination – a brief historical perspective

30 Mar 2009

Abstract excerpt

The high level of protection which can be induced by vaccination of a range of hosts, from rodents to primates, with live radiation-attenuated schistosome larvae offers great promise for development of a human schistosome vaccine. Studies of the irradiated vaccine models benefitted from significant funding during the 1970-90s and much was learned concerning the inducers, targets and mechanisms of immunity. Less...

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PMID: 19327194
DOI: 10.1017/s0031182009005848

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