Article
Ectopic expression of Cvh (Chicken Vasa homologue) mediates the reprogramming of chicken embryonic stem cells to a germ cell fate.
Developmental biology - 1 Jun 2009
Lavial Fabrice, Acloque Hervé, Bachelard Elodie, Nieto M Angela, Samarut Jacques, Pain Bertrand
Abstract excerpt
When they are derived from blastodermal cells of the pre-primitive streak in vitro, the pluripotency of Chicken Embryonic Stem Cells (cESC) can be controlled by the cPouV and Nanog genes. These cESC can differentiate into derivatives of the three germ layers both in vitro and in vivo, but they only weakly colonize the gonads of host embryos. By contrast, non-cultured blastodermal cells and long-term cultured...
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