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Characterisation and Germline Transmission of Cultured Avian Primordial Germ Cells

29 Nov 2010

Abstract excerpt

BACKGROUND: Avian primordial germ cells (PGCs) have significant potential to be used as a cell-based system for the study and preservation of avian germplasm, and the genetic modification of the avian genome. It was previously reported that PGCs from chicken embryos can be propagated in culture and contribute to the germ cell lineage of host birds. PRINCIPAL FINDINGS: We confirm these results by demonstrating...

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PMID: 21124737
DOI: 10.1371/journal.pone.0015518

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