Article

Distinct mechanisms of germ cell factor regulation for an inductive germ cell fate

2022-02-06

Abstract excerpt

Specification of primordial germ cells (PGCs), the lineage which gives rise to eggs and sperm, is essential for sexually reproducing organisms. The mechanism by which animals specify their PGCs generally falls into two categories: inherited or inductive. The inductive mechanism, used by mammals, relies on cell signaling interactions to direct a subset of embryonic cells to a germ cell fate. Previous work suggested...

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Literature Corpus work: 7498d4cd-e579-59f7-81e4-2dda4f1d7292
DOI: 10.1101/2022.02.04.479164

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