Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

To gate or not to gate: using molecular dynamics simulations to morph gated plant aquaporins into constitutively open conformations.

The journal of physical chemistry. B - 16 Apr 2009

Khandelia Himanshu, Jensen Morten Ø, Mouritsen Ole G

Abstract excerpt

The spinach plant aquaporin SoPIP2;1 is a gated water channel, which switches between open and closed states depending on the conformation of a 20-residue cytoplasmic loop, the D-loop. Using fully atomistic molecular dynamics simulations, we have investigated the possibility of driving the confor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aquaporins
Share to Computer Simulation
Share to Lipid Bilayers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Molecular

Share to Osmotic Pressure

Share to Protein Conformation

Share to Spinacia oleracea

Source

Identifiers

PMID: 19320451
DOI: 10.1021/jp809152c

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19320451-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

To gate or not to gate: using molecular dynamics simulations to morph gated plant aquaporins into constitutively open conformations.PMID 19320451Read ↗

Structural and functional analysis of SoPIP2;1 mutants adds insight into plant aquaporin gating.Semantic proximity Read ↗

Water permeation dynamics of AqpZ: a tale of two states.Semantic proximity Read ↗

Control of the selectivity of the aquaporin water channel family by global orientational tuning.Semantic proximity Read ↗

The hidden intricacies of aquaporins: Remarkable details in a common structural scaffoldSemantic proximity Read ↗

Molecular Dynamics Simulations of the Cardiac Ryanodine Receptor Type 2 (RyR2) Gating Mechanism.Semantic proximity Read ↗

Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels.Semantic proximity Read ↗

Molecular Dynamics Simulations of KirBac1.1 Mutants Reveal Global Gating Changes of Kir Channels.Semantic proximity Read ↗

Dynamic interaction of S5 and S6 during voltage-controlled gating in a potassium channel.Semantic proximity Read ↗

Structural basis for pH gating of plant aquaporins.Semantic proximity Read ↗

Interconversion of functional motions between mesophilic and thermophilic adenylate kinases.Semantic proximity Read ↗

Toward the rational design of constitutively active KCa3.1 mutant channels.Semantic proximity Read ↗

Dynamical model of the CLC-2 ion channel reveals conformational changes associated with selectivity-filter gating.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.