Stress-induced premature senescence of endothelial cells: a perilous state between recovery and point of no return

Abstract excerpt

PURPOSE OF REVIEW: To discuss most recently published studies on morphologic patterns and molecular mechanisms of stress-induced premature senescence (SIPS) of vascular endothelial cells. RECENT FINDINGS: Lysosomal dysfunction and impaired autophagy, which have been well established in replicative senescence, were also described in SIPS induced by advanced glycation end products (AGEs). Recently, strides were...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Autophagy in Disease and Therapy
• Share to Caveolin-1 and cellular processes
• Share to Telomeres, Telomerase, and Senescence