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Article

Transcriptional complexes formed by NFAT dimers regulate the induction of T cell tolerance.

The Journal of experimental medicine - 13 Apr 2009

Soto-Nieves Noemi, Puga Irene, Abe Brian T, Bandyopadhyay Sanmay, Baine Ian, Rao Anjana, Macian Fernando

Abstract excerpt

In T cells, anergy can be induced after T cell receptor engagement in the absence of costimulation. Under these conditions, the expression of a specific set of anergy-associated genes is activated. Several lines of evidence suggest that nuclear factor of activated T cells (NFAT) proteins may regulate the expression of many of those genes; however, the nature of the complexes responsible for the induction of this...

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Identifiers

PMID: 19307325
DOI: 10.1084/jem.20082731
PMCID: PMC2715123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Transcriptional complexes formed by NFAT dimers regulate the induction of T cell tolerance.PMID 19307325Read ↗

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