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Article

Sialic acid (N-acetyl neuraminic acid) utilization by Bacteroides fragilis requires a novel N-acetyl mannosamine epimerase.

Journal of bacteriology - 1 Jun 2009

Brigham Christopher, Caughlan Ruth, Gallegos Rene, Dallas Mary Beth, Godoy Veronica G, Malamy Michael H

Abstract excerpt

We characterized the nanLET operon in Bacteroides fragilis, whose products are required for the utilization of the sialic acid N-acetyl neuraminic acid (NANA) as a carbon and energy source. The first gene of the operon is nanL, which codes for an aldolase that cleaves NANA into N-acetyl mannosamine (manNAc) and pyruvate. The next gene, nanE, codes for a manNAc/N-acetylglucosamine (NAG) epimerase, which,...

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Identifiers

PMID: 19304853
DOI: 10.1128/JB.00811-08
PMCID: PMC2681899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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