Article

Identification of an N-acetylneuraminic acid-presenting bacteria isolated from a healthy human microbiome

2020-08-24

Abstract excerpt

N-acetylneuraminic acid is the most abundant sialic acid in humans and is generally expressed as the terminal sugar on intestinal mucus glycans. Several pathogenic bacterial species harvest sialic acid from the mucus, diet, as well as other intestinal sources and display this sugar on their own surface to evade sialic acid-binding immunoglobulin-type lectin (Siglec)-mediated host immune surveillance. While previou...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 814c3676-3748-5147-ae72-b3b6d1a0a971
DOI: 10.1101/2020.08.24.265504

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of an N-acetylneuraminic acid-presenting bacteria isolated from a healthy human microbiomeDOI 10.1101/2020.08.24.265504Read

A bidirectional <i>nanAKE</i> locus enables sialic acid catabolism in gut microbiome member <i>Hungatella hathewayi</i>Semantic proximity Read

Prevotella are major contributors of sialidases in the human vaginal microbiomeSemantic proximity Read

Investigating Host Microbiota Relationships Through Functional MetagenomicsSemantic proximity Read

The group B streptococcal sialic acid O-acetyltransferase is encoded by neuD, a conserved component of bacterial sialic acid biosynthetic gene clusters.Semantic proximity Read

Dysbiosis-associated gut bacterium <i>Ruminococcus gnavus</i> varies at the strain level in ability to utilize key mucin component sialic acidSemantic proximity Read

Discovery and Development of Promiscuous O-Glycan Hydrolases for Removal of Intact Sialyl T-Antigen.Semantic proximity Read

New insights in amino sugar metabolism by the gut microbiomeSemantic proximity Read

Redirection of sialic acid metabolism in genetically engineered Escherichia coli.Semantic proximity Read

Bacterial sialoglycosidases in Virulence and PathogenesisSemantic proximity Read

Human gut metagenomes encode diverse GH156 sialidasesSemantic proximity Read

Uncovering bacterial pseudaminylation with pan-specific antibody toolsSemantic proximity Read

The sweet side of the pathogenic Neisseria: the role of glycan interactions in colonisation and diseaseSemantic proximity Read